- Product Details
Keywords
- CGP36742
- SGS-742
- SGS742
Quick Details
- ProName: CGP36742
- CasNo: 123690-78-8
- Molecular Formula: C7H18NO2P
- Application: treatment of major depressive disorder...
- Port: SH
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- LimitNum: 0 Metric Ton
Superiority
77472-70-9 | phenylpiracetam | |
110958-19-5 | Fasoracetam | |
15180-02-6 | Amfonelic acid | |
68497-62-1 | Pramiracetam | |
116041-13-5 | Nebracetam | |
77191-36-7 | Nefiracetam | |
62613-82-5 | Oxiracetam | |
72432-10-1 | aniracetam | |
157115-85-0 | Noopept | |
59776-89-5 | Piracetam hydrazide | |
51352-87-5 | PRL-8-53 | |
22503-72-6 | IDRA-21 | |
1270138-40-3 | NSI-189 | |
272786-64-8 | Unifiram | |
314728-85-3 | Sunifiram | |
63547-13-7 | Adrafinil | |
33818-15-4 | Citicoline Sodium | |
987-78-0 | Citicoline | |
28319-77-9 | Alpha-GPC | |
120786-18-7 | Huperzine A | |
42971-09-5 | Vinpocetine | |
34271-54-0 | L-theanine | |
38183-03-8 | 7, 8 dihydroxy flavonoids | |
1689-64-1 | 9-fluorenol | |
127464-43-1 |
Mexidol |
Details
Biochem/physiol Actions
CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.